Structural analysis of a series of antiviral agents complexed with human rhinovirus 14.

The binding to human rhinovirus 14 of a series of eight antiviral agents that inhibit picornaviral uncoating after entry into host cells has been characterized crystallographically. All of these bind into the same hydrophobic pocket within the viral protein VP1 beta-barrel structure, although the or...

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Bibliografiske detaljer
Main Authors: Badger, J, Minor, I, Kremer, M J, Oliveira, M A, Smith, T J, Griffith, J P, Guerin, D M, Krishnaswamy, S, Luo, M, Rossmann, M G
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC280197/
https://ncbi.nlm.nih.gov/pubmed/2835768
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