Structural analysis of a series of antiviral agents complexed with human rhinovirus 14.

The binding to human rhinovirus 14 of a series of eight antiviral agents that inhibit picornaviral uncoating after entry into host cells has been characterized crystallographically. All of these bind into the same hydrophobic pocket within the viral protein VP1 beta-barrel structure, although the or...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Badger, J, Minor, I, Kremer, M J, Oliveira, M A, Smith, T J, Griffith, J P, Guerin, D M, Krishnaswamy, S, Luo, M, Rossmann, M G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2835768/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.10.3304
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