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A sequence-specific conformational epitope on U1 RNA is recognized by a unique autoantibody.

An autoantibody from a patient with lupus-overlap syndrome was found to bind a specific region of U1 RNA. By using RNA sequence analysis, immunoprecipitation, and competition experiments with in vitro synthesized fragments of U1 RNA, a region of 40 nucleotides representing a stem-loop secondary stru...

詳細記述

保存先:
書誌詳細
主要な著者: Deutscher, S L, Keene, J D
フォーマット: Artigo
言語:Inglês
出版事項: 1988
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC280196/
https://ncbi.nlm.nih.gov/pubmed/2453054
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