Genome-wide Association Scan Identifies Variants near Matrix Metalloproteinase (MMP) Genes on Chromosome 11q21-22 Strongly Associated with Serum MMP-1 Levels

BACKGROUND: Matrix metalloproteinase 1 (MMP-1) may play a role in cardiovascular disease (CVD) susceptibility by influencing plaque rupture via its ability to degrade extracellular collagens. METHODS AND RESULTS: We performed a genome-wide association analysis of circulating MMP-1 levels using 500K...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cheng, Yu-Ching, Kao, Wen-Hong L., Mitchell, Braxton D., O’Connell, Jeffrey R., Shen, Haiqing, McArdle, Patrick F, Gibson, Quince, Ryan, Kathleen A., Shuldiner, Alan R., Pollin, Toni I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801898/
https://ncbi.nlm.nih.gov/pubmed/20031604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.108.834986
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados