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A mouse model for juvenile doxorubicin-induced cardiac dysfunction

Doxorubicin (DOX) is a potent anti-tumor agent. DOX can also induce cardiotoxicity, and high cumulative doses are associated with recalcitrant heart failure. Children are particularly sensitive to DOX-induced heart failure. The ability to genetically modify mice makes them an ideal experimental syst...

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Bibliografische gegevens
Hoofdauteurs: Zhu, Wuqiang, Shou, Weinian, Payne, R. Mark, Caldwell, Randall, Field, Loren J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801890/
https://ncbi.nlm.nih.gov/pubmed/18614963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e318184d732
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