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A mouse model for juvenile doxorubicin-induced cardiac dysfunction
Doxorubicin (DOX) is a potent anti-tumor agent. DOX can also induce cardiotoxicity, and high cumulative doses are associated with recalcitrant heart failure. Children are particularly sensitive to DOX-induced heart failure. The ability to genetically modify mice makes them an ideal experimental syst...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801890/ https://ncbi.nlm.nih.gov/pubmed/18614963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e318184d732 |
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