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Bradykinin as a pain mediator: receptors are localized to sensory neurons, and antagonists have analgesic actions.

Autoradiographic studies localize [3H]bradykinin receptor binding sites to the substantia gelatinosa, dorsal root, and a subset of small cells in both the dorsal root and trigeminal ganglia of the guinea pig. [3H]Bradykinin labeling is also observed over myocardial/coronary visceral afferent fibers....

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Bibliographic Details
Main Authors: Steranka, L R, Manning, D C, DeHaas, C J, Ferkany, J W, Borosky, S A, Connor, J R, Vavrek, R J, Stewart, J M, Snyder, S H
Format: Artigo
Language:Inglês
Published: 1988
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC280181/
https://ncbi.nlm.nih.gov/pubmed/2896357
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