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Bradykinin as a pain mediator: receptors are localized to sensory neurons, and antagonists have analgesic actions.

Autoradiographic studies localize [3H]bradykinin receptor binding sites to the substantia gelatinosa, dorsal root, and a subset of small cells in both the dorsal root and trigeminal ganglia of the guinea pig. [3H]Bradykinin labeling is also observed over myocardial/coronary visceral afferent fibers....

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Steranka, L R, Manning, D C, DeHaas, C J, Ferkany, J W, Borosky, S A, Connor, J R, Vavrek, R J, Stewart, J M, Snyder, S H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280181/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2896357/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.9.3245
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