The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis

BACKGROUND: Tumor development in the human colon is commonly accompanied by epigenetic changes, such as DNA methylation and chromatin modifications. These alterations result in significant, inheritable changes in gene expression that contribute to the selection of tumor cells with enhanced survival...

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Autores principales: Menigatti, Mirco, Cattaneo, Elisa, Sabates-Bellver, Jacob, Ilinsky, Valery V, Went, Philip, Buffoli, Federico, Marquez, Victor E, Jiricny, Josef, Marra, Giancarlo
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801661/
https://ncbi.nlm.nih.gov/pubmed/20015382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-124
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