The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis

BACKGROUND: Tumor development in the human colon is commonly accompanied by epigenetic changes, such as DNA methylation and chromatin modifications. These alterations result in significant, inheritable changes in gene expression that contribute to the selection of tumor cells with enhanced survival...

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Autors principals: Menigatti, Mirco, Cattaneo, Elisa, Sabates-Bellver, Jacob, Ilinsky, Valery V, Went, Philip, Buffoli, Federico, Marquez, Victor E, Jiricny, Josef, Marra, Giancarlo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801661/
https://ncbi.nlm.nih.gov/pubmed/20015382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-124
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