The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis

BACKGROUND: Tumor development in the human colon is commonly accompanied by epigenetic changes, such as DNA methylation and chromatin modifications. These alterations result in significant, inheritable changes in gene expression that contribute to the selection of tumor cells with enhanced survival...

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Detalhes bibliográficos
Main Authors: Menigatti, Mirco, Cattaneo, Elisa, Sabates-Bellver, Jacob, Ilinsky, Valery V, Went, Philip, Buffoli, Federico, Marquez, Victor E, Jiricny, Josef, Marra, Giancarlo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801661/
https://ncbi.nlm.nih.gov/pubmed/20015382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-124
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