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IL-21 preferentially enhances IL-15-mediated homeostatic proliferation of human CD28(+) CD8 memory T cells throughout the adult age span
An age-related decline in human immune response is marked by the accumulation of CD28(–) CD8 T cells, which is attributed to repeated antigenic stimulation and to homeostatic proliferation mediated by cytokines such as IL-15. However, the identity of the cytokines that are responsible for the mainte...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Society for Leukocyte Biology
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801617/ https://ncbi.nlm.nih.gov/pubmed/19797296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0209086 |
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