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Transgenic rabbits with lymphocytic leukemia induced by the c-myc oncogene fused with the immunoglobulin heavy chain enhancer.

Transgenic rabbits with the rabbit c-myc oncogene fused with the rabbit immunoglobulin heavy chain enhancer region (E mu) DNA were developed by microinjecting pronuclei of single cell zygotes with the gene construct and implanting the microinjected eggs into pseudopregnant females. At age 17-20 days...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Knight, K L, Spieker-Polet, H, Kazdin, D S, Oi, V T
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1988
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2834733/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.9.3130
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