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A Multifactorial Mechanism in the Superior Antimalarial Activity of α-C-GalCer

We have previously shown that the C-glycoside analog of α-galactosylceramide (α-GalCer), α-C-GalCer, displays a superior inhibitory activity against the liver stages of the rodent malaria parasite Plasmodium yoelii than its parental glycolipid, α-GalCer. In this study, we demonstrate that NK cells,...

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Main Authors: Schmieg, John, Yang, Guangli, Franck, Richard W., Tsuji, Moriya
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801455/
https://ncbi.nlm.nih.gov/pubmed/20069056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/283612
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