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Aberrant planar cell polarity induced by urinary tract obstruction
Flow sensing by primary cilia of the epithelial cells is involved in cystogenesis in polycystic kidney disease. We investigate whether a similar mechanism applies to the pathogenesis of cyst-like tubular dilatation induced by ureteral obstruction in mice. Robust proliferation occurs in the obstructe...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801343/ https://ncbi.nlm.nih.gov/pubmed/19794107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00318.2009 |
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