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Oxidative stress-induced JNK activation contributes to proinflammatory phenotype of aging diabetic mesangial cells
Chronic inflammation and increased oxidative stress (OS) play an important role in diabetic nephropathy progression. Herein, we show that mesangial cells from streptozotocin-induced aging diabetic mice, a model of progressive diabetic nephropathy, exhibited increased OS and a proinflammatory phenoty...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801342/ https://ncbi.nlm.nih.gov/pubmed/19776174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00078.2009 |
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