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Oral Glycotoxins Determine the Effects of Calorie Restriction on Oxidant Stress, Age-Related Diseases, and Lifespan

We previously showed that the content of advanced glycation end products (AGEs) in the diet correlates with serum AGE levels, oxidant stress (OS), organ dysfunction, and lifespan. We now show that the addition of a chemically defined AGE (methyl-glyoxal-BSA) to low-AGE mouse chow increased serum lev...

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Autors principals: Cai, Weijing, He, John C., Zhu, Li, Chen, Xue, Zheng, Feng, Striker, Gary E., Vlassara, Helen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475771/
https://ncbi.nlm.nih.gov/pubmed/18599606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080152
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