Excessive Oxidative Stress Contributes to Increased Acute ER Stress Kidney Injury in Aged Mice

The aged kidney is susceptible to acute injury due presumably to its decreased ability to handle additional challenges, such as endoplasmic reticulum (ER) stress. This was tested by giving tunicamycin, an ER stress inducer, to either old or young mice. Injection of high dose caused renal failure in...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Liu, Xiaoyan, Zhang, Ruihua, Huang, Lianghu, Zheng, Zihan, Vlassara, Helen, Striker, Gary, Zhang, Xiaoyan, Guan, Youfei, Zheng, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369482/
https://ncbi.nlm.nih.gov/pubmed/30809321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2746521
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