Distinct Roles for Rho Versus Rac/Cdc42 GTPases Downstream of Vav2 in Regulating Mammary Epithelial Acinar Architecture

Non-malignant mammary epithelial cells (MECs) undergo acinar morphogenesis in three-dimensional Matrigel culture, a trait that is lost upon oncogenic transformation. Rho GTPases are thought to play important roles in regulating epithelial cell-cell junctions, but their contributions to acinar morpho...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Duan, Lei, Chen, Gengsheng, Virmani, Sumeet, Ying, GuoGuang, Raja, Srikumar M., Chung, Byung Min, Rainey, Mark A., Dimri, Manjari, Ortega-Cava, Cesar F., Zhao, Xiangshan, Clubb, Robert J., Tu, Chun, Reddi, Alagarsamy L., Naramura, Mayumi, Band, Vimla, Band, Hamid
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801280/
https://ncbi.nlm.nih.gov/pubmed/19826000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.057976
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky