Large T Antigen Promotes JC Virus Replication in G(2)-arrested Cells by Inducing ATM- and ATR-mediated G(2) Checkpoint Signaling

Large T antigen (TAg) of the human polyomavirus JC virus (JCV) possesses DNA binding and helicase activities, which, together with various cellular proteins, are required for replication of the viral genome. We now show that JCV-infected cells expressing TAg accumulate in the G(2) phase of the cell...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Orba, Yasuko, Suzuki, Tadaki, Makino, Yoshinori, Kubota, Kanako, Tanaka, Shinya, Kimura, Takashi, Sawa, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801279/
https://ncbi.nlm.nih.gov/pubmed/19903823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.064311
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados