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Each Monomer of the Dimeric Accessory Protein for Human Mitochondrial DNA Polymerase Has a Distinct Role in Conferring Processivity

The accessory protein polymerase (pol) γB of the human mitochondrial DNA polymerase stimulates the synthetic activity of the catalytic subunit. pol γB functions by both accelerating the polymerization rate and enhancing polymerase-DNA interaction, thereby distinguishing itself from the accessory sub...

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Autores principales: Lee, Young-Sam, Lee, Sujin, Demeler, Borries, Molineux, Ian J., Johnson, Kenneth A., Yin, Y. Whitney
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801274/
https://ncbi.nlm.nih.gov/pubmed/19858216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.062752
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