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Each Monomer of the Dimeric Accessory Protein for Human Mitochondrial DNA Polymerase Has a Distinct Role in Conferring Processivity

The accessory protein polymerase (pol) γB of the human mitochondrial DNA polymerase stimulates the synthetic activity of the catalytic subunit. pol γB functions by both accelerating the polymerization rate and enhancing polymerase-DNA interaction, thereby distinguishing itself from the accessory sub...

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Autors principals: Lee, Young-Sam, Lee, Sujin, Demeler, Borries, Molineux, Ian J., Johnson, Kenneth A., Yin, Y. Whitney
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801274/
https://ncbi.nlm.nih.gov/pubmed/19858216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.062752
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