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α(1A/B)-Knockout mice explain the native α(1D)-adrenoceptor's role in vasoconstriction and show that its location is independent of the other α(1)-subtypes

BACKGROUND AND PURPOSE: Theoretically, three α(1)-adrenoceptor subtypes can interact at the signalling level to alter vascular contraction or at the molecular level to alter each other's cellular location. The α(1A/B)-adrenoceptor knockout mouse (α(1A/B)-KO) was used to study the isolated α(1D)...

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Autors principals: Methven, L, Simpson, PC, McGrath, JC
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801207/
https://ncbi.nlm.nih.gov/pubmed/19888965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00462.x
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