The α(1B/D)-adrenoceptor knockout mouse permits isolation of the vascular α(1A)-adrenoceptor and elucidates its relationship to the other subtypes

BACKGROUND AND PURPOSE: Mesenteric and carotid arteries from the α(1B/D)-adrenoceptor knockout (α(1B/D)-KO) were employed to isolate α(1A)-adrenoceptor pharmacology and location and to reveal these features in the wild-type (WT) mouse. EXPERIMENTAL APPROACH: Functional pharmacology by wire myography...

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Hlavní autoři: Methven, L, McBride, M, Wallace, GA, McGrath, JC
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2009
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795267/
https://ncbi.nlm.nih.gov/pubmed/19572943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00269.x
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