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The α(1B/D)-adrenoceptor knockout mouse permits isolation of the vascular α(1A)-adrenoceptor and elucidates its relationship to the other subtypes
BACKGROUND AND PURPOSE: Mesenteric and carotid arteries from the α(1B/D)-adrenoceptor knockout (α(1B/D)-KO) were employed to isolate α(1A)-adrenoceptor pharmacology and location and to reveal these features in the wild-type (WT) mouse. EXPERIMENTAL APPROACH: Functional pharmacology by wire myography...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795267/ https://ncbi.nlm.nih.gov/pubmed/19572943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00269.x |
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