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Lack of Association of the TP53 Arg72Pro SNP and the MDM2 SNP309 with systemic lupus erythematosus in Caucasian, African American, and Asian children and adults

The p53 tumour suppressor is the central regulator of apoptosis. Previously, the functional TP53 Arg72Pro polymorphism was found to be associated with systemic lupus erythematosus (SLE) in Koreans but not Spaniards. MDM2 is the major negative regulator of p53. An intronic polymorphism in MDM2, the S...

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Main Authors: Onel, KB, Huo, D, Hastings, D, Fryer-Biggs, J, Crow, MK, Onel, K
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801155/
https://ncbi.nlm.nih.gov/pubmed/19074170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0961203308094558
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