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Apex1 can cleave complex clustered DNA lesions in cells
Current data indicate that clustered DNA damage generated by ionizing radiation contains 2–5 damages within 20 bps. The complexity of clustered damage is also believed to increase as the linear energy transfer of the radiation increases. Complex lesions are therefore biologically relevant especially...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801153/ https://ncbi.nlm.nih.gov/pubmed/19800300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.08.008 |
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