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Power of multifactor dimensionality reduction and penalized logistic regression for detecting gene-gene Interaction in a case-control study

BACKGROUND: There is a growing awareness that interaction between multiple genes play an important role in the risk of common, complex multi-factorial diseases. Many common diseases are affected by certain genotype combinations (associated with some genes and their interactions). The identification...

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Detalhes bibliográficos
Main Authors: He, Hua, Oetting, William S, Brott, Marcia J, Basu, Saonli
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800840/
https://ncbi.nlm.nih.gov/pubmed/19961594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-10-127
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