An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene Interactions on risk of myocardial infarction: The importance of model validation

BACKGROUND: To examine interactions among the angiotensin converting enzyme (ACE) insertion/deletion, plasminogen activator inhibitor-1 (PAI-1) 4G/5G, and tissue plasminogen activator (t-PA) insertion/deletion gene polymorphisms on risk of myocardial infarction using data from 343 matched case-contr...

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Main Authors: Coffey, Christopher S, Hebert, Patricia R, Ritchie, Marylyn D, Krumholz, Harlan M, Gaziano, J Michael, Ridker, Paul M, Brown, Nancy J, Vaughan, Douglas E, Moore, Jason H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419697/
https://ncbi.nlm.nih.gov/pubmed/15119966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-5-49
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