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Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma.

We show that endemic (eBL), sporadic (sBL), and acquired immunodeficiency syndrome-associated (AIDS-BL) forms of Burkitt lymphoma (BL) carrying t(8;14) chromosomal translocations display different breakpoints within the immunoglobulin heavy-chain locus (IGH) on chromosome 14. In sBL (7 out of 11) an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Neri, A, Barriga, F, Knowles, D M, Magrath, I T, Dalla-Favera, R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280076/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2833750/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.8.2748
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