Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma.

We show that endemic (eBL), sporadic (sBL), and acquired immunodeficiency syndrome-associated (AIDS-BL) forms of Burkitt lymphoma (BL) carrying t(8;14) chromosomal translocations display different breakpoints within the immunoglobulin heavy-chain locus (IGH) on chromosome 14. In sBL (7 out of 11) an...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Neri, A, Barriga, F, Knowles, D M, Magrath, I T, Dalla-Favera, R
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1988
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280076/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2833750/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.8.2748
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