Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma.

We show that endemic (eBL), sporadic (sBL), and acquired immunodeficiency syndrome-associated (AIDS-BL) forms of Burkitt lymphoma (BL) carrying t(8;14) chromosomal translocations display different breakpoints within the immunoglobulin heavy-chain locus (IGH) on chromosome 14. In sBL (7 out of 11) an...

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Hauptverfasser: Neri, A, Barriga, F, Knowles, D M, Magrath, I T, Dalla-Favera, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC280076/
https://ncbi.nlm.nih.gov/pubmed/2833750
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