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Use of synthetic oligonucleotides for genomic DNA dot hybridization to split the DQw3 haplotype.

Comparison of two different HLA-DQ beta gene sequences from two DR4 individuals, probably corresponding to DQw3.2 (DQR4) and DQw3.1 (DQR5) specificities, has shown several nucleotide variations. Eight oligonucleotides (24 bases long), derived from these polymorphic areas, have been synthesized. Each...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Martell, M, Le Gall, I, Millasseau, P, Dausset, J, Cohen, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2895927/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.8.2682
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