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Non-Traditional Platinum Compounds for Improved Accumulation, Oral Bioavailability, and Tumor Targeting
The five platinum anticancer compounds currently in clinical use conform to structure-activity relationships formulated1 shortly after the discovery2 that cis-diamminedichloroplatinum(II), cisplatin, has antitumor activity in mice. These compounds are neutral, platinum(II) species with two am(m)ine...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2800312/ https://ncbi.nlm.nih.gov/pubmed/20023892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b913896j |
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