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Conjugated Platinum(IV)-Peptide Complexes for Targeting Angiogenic Tumor Vasculature
The integrins α(v)β(3) and α(v)β(5) and the membrane-spanning surface protein aminopeptidase-N (APN) are highly expressed in tumor-induced angiogenesis, making them attractive targets for therapeutic intervention. Both integrins and APN recognize a broad range of peptides containing RGD (Arg-Gly-Asp...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2505196/ https://ncbi.nlm.nih.gov/pubmed/17845003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc070031k |
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