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Discovery Properties of Genome-wide Association Signals From Cumulatively Combined Data Sets

Genetic effects for common variants affecting complex disease risk are subtle. Single genome-wide association (GWA) studies are typically underpowered to detect these effects, and combination of several GWA data sets is needed to enhance discovery. The authors investigated the properties of the disc...

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Hlavní autoři: Pereira, Tiago V., Patsopoulos, Nikolaos A., Salanti, Georgia, Ioannidis, John P. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800267/
https://ncbi.nlm.nih.gov/pubmed/19808636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwp262
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