The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

An RNA-dependent RNA polymerase (RdRp) is the central catalytic subunit of the RNA-synthesizing machinery of all positive-strand RNA viruses. Usually, RdRp domains are readily identifiable by comparative sequence analysis, but biochemical confirmation and characterization can be hampered by intrinsi...

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Autores principales: te Velthuis, Aartjan J. W., Arnold, Jamie J., Cameron, Craig E., van den Worm, Sjoerd H. E., Snijder, Eric J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800238/
https://ncbi.nlm.nih.gov/pubmed/19875418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp904
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