HMGB1 is a Co-factor in Mammalian Base Excision Repair

Deoxyribose phosphate (dRP) removal by DNA polymerase β(Pol β) is a pivotal step in base excision repair (BER). To identify novel BER co-factors, especially those with dRP lyase activity, we used a Pol β null cell extract and BER intermediate as bait for sodium borohydride cross-linking. Mass spectr...

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Autori principali: Prasad, Rajendra, Liu, Yuan, Deterding, Leesa J., Poltoratsky, Vladimir P., Kedar, Padmini S., Horton, Julie K., Kanno, Shin-ichiro, Asagoshi, Kenjiro, Hou, Esther W., Khodyreva, Svetlana N., Lavrik, Olga I., Tomer, Kenneth B., Yasui, Akira, Wilson, Samuel H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799894/
https://ncbi.nlm.nih.gov/pubmed/17803946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.06.029
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