Alterations of the Notch pathway in lung cancer

Notch signaling regulates cell specification and homeostasis of stem cell compartments, and it is counteracted by the cell fate determinant Numb. Both Numb and Notch have been implicated in human tumors. Here, we show that Notch signaling is altered in approximately one third of non–small-cell lung...

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Detalhes bibliográficos
Main Authors: Westhoff, Britta, Colaluca, Ivan N., D'Ario, Giovanni, Donzelli, Maddalena, Tosoni, Daniela, Volorio, Sara, Pelosi, Giuseppe, Spaggiari, Lorenzo, Mazzarol, Giovanni, Viale, Giuseppe, Pece, Salvatore, Di Fiore, Pier Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799768/
https://ncbi.nlm.nih.gov/pubmed/20007775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907781106
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