The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency

Dmrt1 (doublesex and mab-3 related transcription factor 1) is a conserved transcriptional regulator of male differentiation required for testicular development in vertebrates. Here, we show that in mice of the 129Sv strain, loss of Dmrt1 causes a high incidence of teratomas, whereas these tumors do...

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Detalhes bibliográficos
Main Authors: Krentz, Anthony D., Murphy, Mark W., Kim, Shinseog, Cook, Matthew S., Capel, Blanche, Zhu, Rui, Matin, Angabin, Sarver, Aaron L., Parker, Keith L., Griswold, Michael D., Looijenga, Leendert H. J., Bardwell, Vivian J., Zarkower, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799724/
https://ncbi.nlm.nih.gov/pubmed/20007774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905431106
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