The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency

Dmrt1 (doublesex and mab-3 related transcription factor 1) is a conserved transcriptional regulator of male differentiation required for testicular development in vertebrates. Here, we show that in mice of the 129Sv strain, loss of Dmrt1 causes a high incidence of teratomas, whereas these tumors do...

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Autors principals: Krentz, Anthony D., Murphy, Mark W., Kim, Shinseog, Cook, Matthew S., Capel, Blanche, Zhu, Rui, Matin, Angabin, Sarver, Aaron L., Parker, Keith L., Griswold, Michael D., Looijenga, Leendert H. J., Bardwell, Vivian J., Zarkower, David
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799724/
https://ncbi.nlm.nih.gov/pubmed/20007774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905431106
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