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Pharmacological Targeting of the Hsp70 Chaperone

The molecular chaperone, heat shock protein 70 (Hsp70), acts at multiple steps in a protein’s life cycle, including during the processes of folding, trafficking, remodeling and degradation. To accomplish these various tasks, the activity of Hsp70 is shaped by a host of co-chaperones, which bind to t...

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Autores principales: Patury, Srikanth, Miyata, Yoshinari, Gestwicki, Jason E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799686/
https://ncbi.nlm.nih.gov/pubmed/19860737
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