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Reduced Pressure Ice Fog Technique for Controlled Ice Nucleation during Freeze-Drying
A method to achieve controlled ice nucleation during the freeze-drying process using an ice fog technique was demonstrated in an earlier report. However, the time required for nucleation was about 5 min, even though only one shelf was used, which resulted in Ostwald ripening (annealing) in some of t...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer US
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799604/ https://ncbi.nlm.nih.gov/pubmed/19937284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9338-7 |
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