Neuroprotection Against Hypoxic-Ischemic Brain Injury by Inhibiting the Apoptotic Protease Activating Factor-1 Pathway

OBJECTIVES: Emerging evidence suggests that mitochondrial damage-mediated neuronal apoptosis is a major contributor to neonatal hypoxic-ischemic (H-I) brain injury. This study was performed to determine whether targeted inhibition of the apoptotic protease activating factor-1 (Apaf-1) signaling path...

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Hlavní autoři: Gao, Yanqin, Liang, Weimin, Hu, Xiaoming, Zhang, Wenting, Stetler, R. Anne, Vosler, Peter, Cao, Guodong, Chen, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799533/
https://ncbi.nlm.nih.gov/pubmed/19910549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.561852
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