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Nonsense mutations in the human beta-globin gene affect mRNA metabolism.
A number of premature translation termination mutations (nonsense mutations) have been described in the human alpha- and beta-globin genes. Studies on mRNA isolated from patients with beta zero-thalassemia have shown that for both the beta-17 and the beta-39 mutations less than normal levels of beta...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3353367/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.7.2056 |
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