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Nonsense mutations in the human beta-globin gene affect mRNA metabolism.

A number of premature translation termination mutations (nonsense mutations) have been described in the human alpha- and beta-globin genes. Studies on mRNA isolated from patients with beta zero-thalassemia have shown that for both the beta-17 and the beta-39 mutations less than normal levels of beta...

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Dettagli Bibliografici
Autori principali: Baserga, S J, Benz, E J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1988
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC279927/
https://ncbi.nlm.nih.gov/pubmed/3353367
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