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Randomized Double-Blind 2 × 2 Trial of Low-Dose Tamoxifen and Fenretinide for Breast Cancer Prevention in High-Risk Premenopausal Women

PURPOSE: Tamoxifen and fenretinide are active in reducing premenopausal breast cancer risk and work synergistically in preclinical models. The authors assessed their combination in a two-by-two biomarker trial. PATIENTS AND METHODS: A total of 235 premenopausal women with pT1mic/pT1a breast cancer (...

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Detalhes bibliográficos
Main Authors: Decensi, Andrea, Robertson, Chris, Guerrieri-Gonzaga, Aliana, Serrano, Davide, Cazzaniga, Massimiliano, Mora, Serena, Gulisano, Marcella, Johansson, Harriet, Galimberti, Viviana, Cassano, Enrico, Moroni, Simona M., Formelli, Franca, Lien, Ernst A., Pelosi, Giuseppe, Johnson, Karen A., Bonanni, Bernardo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799048/
https://ncbi.nlm.nih.gov/pubmed/19597031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.19.3797
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