A randomized phase II presurgical trial of weekly low-dose tamoxifen versus raloxifene versus placebo in premenopausal women with estrogen receptor-positive breast cancer

INTRODUCTION: We previously demonstrated that 1 or 5 mg per day of tamoxifen (T) given for four weeks before surgery reduces Ki-67 in breast cancer (BC) patients to the same extent as the standard 20 mg/d. Given the long half-life of T, a weekly dose (10 mg per week (w)) may be worth testing. Also,...

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Detalhes bibliográficos
Main Authors: Serrano, Davide, Lazzeroni, Matteo, Gandini, Sara, Macis, Debora, Johansson, Harriet, Gjerde, Jennifer, Lien, Ernst, Feroce, Irene, Pruneri, Giancarlo, Sandri, Maria Teresa, Bassi, Fabio, Brenelli, Fabricio, Luini, Alberto, Cazzaniga, Massimiliano, Varricchio, Clara, Guerrieri-Gonzaga, Aliana, DeCensi, Andrea, Bonanni, Bernardo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053157/
https://ncbi.nlm.nih.gov/pubmed/23786776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3439
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