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Structural and dynamic implications of an effector-induced backbone amide cis-trans isomerization in cytochrome P450(cam)
Experimental evidence has been provided for a functionally relevant cis-trans isomerization of the Ile 88-Pro 89 peptide bond in cytochrome P450(cam) (CYP101). The isomerization is proposed to be a key element of the structural reorganization leading to the catalytically competent form of CYP101 upo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799046/ https://ncbi.nlm.nih.gov/pubmed/19327368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.03.046 |
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