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Spring-loading the active site of cytochrome P450(cam)
A hydrogen bond network has been identified that adjusts protein-substrate contacts in cytochrome P450(cam) (CYP101A1). Replacing the native substrate camphor with adamantanone or norcamphor causes perturbations in NMR-detected NH correlations assigned to the network, which includes portions of aβ s...
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| Hoofdauteurs: | , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071453/ https://ncbi.nlm.nih.gov/pubmed/21186391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mt00065e |
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