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Spring-loading the active site of cytochrome P450(cam)

A hydrogen bond network has been identified that adjusts protein-substrate contacts in cytochrome P450(cam) (CYP101A1). Replacing the native substrate camphor with adamantanone or norcamphor causes perturbations in NMR-detected NH correlations assigned to the network, which includes portions of aβ s...

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Detalhes bibliográficos
Main Authors: Dang, Marina, Pochapsky, Susan Sondej, Pochapsky, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071453/
https://ncbi.nlm.nih.gov/pubmed/21186391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mt00065e
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