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Herpes simplex virus blocks apoptosis by precluding mitochondrial cytochrome c release independent of caspase activation in infected human epithelial cells

Expression of HSV-1 genes leads to the induction of apoptosis in human epithelial HEp-2 cells but the subsequent synthesis of infected cell protein prevents the process from killing the cells. Thus, viruses unable to produce appropriate prevention factors are apoptotic. We now report that the additi...

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Autores principales: Aubert, Martine, Pomeranz, Lisa E., Blaho, John A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Kluwer Academic Publishers 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799008/
https://ncbi.nlm.nih.gov/pubmed/17080326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-006-0330-3
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