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Accumulation of Herpes Simplex Virus Type 1 Early and Leaky-Late Proteins Correlates with Apoptosis Prevention in Infected Human HEp-2 Cells

We previously reported that a recombinant ICP27-null virus stimulated, but did not prevent, apoptosis in human HEp-2 cells during infection (M. Aubert and J. A. Blaho, J. Virol. 73:2803–2813, 1999). In the present study, we used a panel of 15 recombinant ICP27 mutant viruses to determine which featu...

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Detalhes bibliográficos
Main Authors: Aubert, Martine, Rice, Stephen A., Blaho, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113998/
https://ncbi.nlm.nih.gov/pubmed/11134315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.2.1013-1030.2001
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